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Clozapine and Tobacco Smoke: How Smoking Changes Your Medication Levels

Clozapine and Tobacco Smoke: How Smoking Changes Your Medication Levels

Smoking can reduce clozapine levels by up to 50%, risking relapse or toxicity. Learn how CYP1A2 enzyme induction works, why dose adjustments are critical, and what to ask your doctor if you smoke or quit.

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Nov 24, 2025 by callum wilson

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