Cyproheptadine: Quick Guide for Patients and Professionals

When talking about Cyproheptadine, a first‑generation antihistamine that also blocks serotonin receptors. Also known as Periactin, it acts on histamine H1 and serotonin 5‑HT2 receptors, making it useful for allergy relief and appetite stimulation. In the same breath, Antihistamine refers to any drug that counters histamine‑mediated symptoms, while Serotonin antagonist describes compounds that inhibit serotonin activity in the brain. Together, these roles let Cyproheptadine tackle multiple health challenges.

Key Benefits, Typical Doses, and Safety Tips

Because it’s both an Appetite stimulant and a reliable Migraine prophylaxis agent, doctors often prescribe it for patients who struggle to gain weight or who need preventive migraine therapy. The usual adult dose for allergy symptoms starts at 4 mg once daily, gradually rising to 8 mg split into two doses if needed. For appetite increase, pediatric dosing follows weight‑based guidelines, typically 0.25 mg/kg per day in divided doses. Side effects most people notice are drowsiness, dry mouth and occasionally weight gain. Rarely, patients report visual disturbances or elevated liver enzymes, so routine blood work is wise for long‑term use. Interactions matter: combining Cyproheptadine with other sedatives, monoamine oxidase inhibitors (MAOIs) or serotonergic drugs can amplify CNS depression or serotonin syndrome. Always double‑check with a pharmacist before adding over‑the‑counter sleep aids or herbal supplements.

Beyond the basics, this page pulls together everything you need to decide if Cyproheptadine fits your health plan. Below you’ll find in‑depth articles covering allergy management, appetite‑boosting strategies, migraine prevention protocols, and safety checklists for drug interactions. Whether you’re a patient looking for clear dosing advice or a clinician needing a quick reference, the collection gives you practical insights you can act on right away.